San Francisco remains one of the world's leading technology hubs, home to innovative startups, enterprise companies, and digital-first brands. As businesses increasingly adopt composable commerce, Medusa.js has become a popular open-source commerce platform for building highly customizable, scalable, and API-first eCommerce solutions.

Whether you're launching a new online marketplace, migrating from a legacy commerce platform, or building a headless commerce architecture, partnering with an experienced Medusa.js agency can help you accelerate development and future-proof your eCommerce stack.

Here are the Top 3 Medusa.js Agencies in San Francisco for 2026, selected based on their expertise in headless commerce, modern web technologies, and enterprise eCommerce development.

1. Weframe Tech

Weframe Tech The Top Rated Medusa.js Development Agency on Upwork, Serving Clients Globally.

Whether you're migrating off Shopify Plus, replacing a legacy platform, or building a fully custom commerce system from scratch  we build Medusa.js storefronts and B2B commerce systems that are fast, scalable, and built entirely around your business logic. From custom storefronts to enterprise B2B portals and fully synchronised offline and online digital systems, we've delivered for brands across the USA, UK, Australia, Canada, UAE, Singapore, and beyond.

Why Brands Choose Weframe Tech for Medusa.js

We don't just implement Medusa.js. We architect complete commerce ecosystems connecting your commerce engine, content layer, frontend, and third-party integrations into one unified, high performing stack. We are recognised as one of the best Medusa.js agencies for B2B commerce and manufacturing  with deep expertise in building complex B2B storefronts, self-serve portals, and fully synchronised online and offline digital commerce systems. Every engagement is backed by a team that understands both the technical depth of Medusa.js and the commercial outcomes your business demands.

What We Build

• Custom Medusa.js Storefronts — fully bespoke, brand-first commerce experiences built from the ground up

• Medusa.js + Next.js /Nuxt JS /Astro JS Storefront — server-side rendered, SEO-dominant, and blazing fast custom storefronts

• Medusa.js + Sanity CMS/Directus CMS/Strapi  — full content and commerce control in one unified stack

• B2B Storefronts & Portals — account-level pricing, role-based access, quote workflows, PO-based checkout, and net payment terms

• Offline & Online Sync — ERP-connected order management, real-time inventory sync, and unified customer data across all channels

• Manufacturing Commerce Systems — configure-to-order, make-to-order, dealer and distributor network management

• Medusa.js B2B & Wholesale — tiered pricing, bulk ordering, contract pricing, and customer-group-specific catalogues

• Medusa.js Migration — seamless migrations from Shopify, WooCommerce, Magento, BigCommerce, or any legacy platform

• Medusa.js Plugin & Module Development — custom plugins, workflows, and modules built for your exact business logic

• Medusa.js Internationalisation — multi-currency, multi-language, and multi-region setups for global brands

• Ongoing Retainer & Growth Support — a dedicated team that continues to optimise, extend, and grow your implementation post-launch

Why WeframeTech

Our Medusa.js Tech Stack

Commerce Engine Medusa.js v2, Medusa.js Modules, Custom Plugins & Workflows

Frontend Frameworks Next.js, Nuxt.js, Astro.js, Remix, SvelteKit

CMS & Content Sanity CMS, Contentful, Storyblok, DatoCMS, Prismic,Directus CMS

PIM Akeneo, Salsify, Pimcore, inRiver, Plytix

Search & Discovery Algolia, Meilisearch, Elasticsearch, Constructor.io, Bloomreach

Reviews & Social Proof Okendo, Yotpo, Stamped, Judge.me

Subscriptions & Loyalty Recharge, Loyalty Lion, Smile.io

Email & Retention Klaviyo, Omnisend, ActiveCampaign, Customer.io

Analytics & CRO Google Analytics 4, Hotjar, FullStory, Heap, Microsoft Clarity, Triple Whale

Personalisation & A/B Testing Optimizely, VWO, Dynamic Yield, Ninetailed, AB Tasty

Customer Data & CDP Segment, Rudderstack, Bloomreach CDP, Klaviyo

Payments & Checkout Stripe, PayPal, Klarna, Afterpay, Braintree, Adyen, Mollie

OMS & Fulfilment ShipBob, Shipstation, Brightpearl, Fluent Commerce, Orderhive

ERP & Backend SAP, Oracle NetSuite, Microsoft Dynamics 365, Acumatica, Brightpearl

EDI & Supply Chain SPS Commerce, TrueCommerce, DiCentral

Infrastructure & DevOps Vercel, Netlify, AWS, Railway, Docker, GitHub Actions, Cloudflare

Design & Prototyping Figma, Framer, Adobe XD, Lottie

Who We Work With

We work with DTC brands, enterprise retailers, B2B operators, manufacturers, and high-growth businesses that have outgrown their current platform and need something built exactly for them. Our clients include:

• Certify — $50M funded healthcare company

• Slingshotbio.com — $49M funded biotech company

• Unimig — Australia's largest welding manufacturer

• Skin Laundry — One of the largest skin treatment brands in the USA, $3M+ venture funded

• Abaxx Exchange — Publicly listed fintech company

• Catalyser

We've also had the privilege of working with globally recognised brands including Ferrari, Bentley, Keepway, Lulu Mall, and Bellini.

Where We Work

We are a globally distributed agency serving clients across:

• 🇺🇸 United States

• 🇬🇧 United Kingdom

• 🇦🇺 Australia

• 🇨🇦 Canada

• 🇦🇪 United Arab Emirates

• 🇸🇬 Singapore

• 🇪🇺 Europe

• 🇮🇳 India

No matter where you are — our team operates across time zones to deliver without delay.

Key areas we help with:

• Future-proof ecommerce tech stack to help you solve for slow sites, better A/B testing, reduce TCO, optimize for scaling

• Improve omnichannel consistency and unify online and offline customer data

• Improve customer experience (CX)

• Reduce operational costs

• Increase AOV

• Reduce CAC

• Increase conversion rates

•  Migration 

Here's how we typically engage:

• We start with a mandatory 30-minute discovery call to understand your vision, goals, growth plans, and current challenges

• We help solve business-facing issues like poor AI and SEO visibility, low conversion rates, low AOV, and scaling to different countries by introducing systems like headless CMS and better composable eCommerce solutions built to address these challenges

• Beyond development, we've helped companies scale strategically by optimizing for SEO, performance, and long-term growth

If Any of These Sound Familiar — We Should Talk

• You're paying too much in Shopify Plus or Commercetools licensing fees

• Your current platform can't support your custom business logic without expensive workarounds

• You need full ownership of your commerce stack  code, data, and infrastructure

• You're a manufacturer or B2B operator who needs a portal, not just a storefront

• You need offline and online systems fully synchronised in real time

• You're planning a migration and need a team that has done it at scale

• You need a long-term technical partner, not just a one-time implementation team

Every project we take on is treated as a commercial problem first and a technical one second. We don't just implement Medusa.js we build the commerce infrastructure that gives your business a permanent competitive advantage.

2. Rigby

Rigby is a San Francisco-based digital product and software development agency that helps businesses build modern eCommerce experiences using technologies such as Medusa.js, Next.js, React, and Node.js. The agency specializes in creating scalable, API-first commerce solutions tailored to the unique needs of startups, direct-to-consumer brands, and enterprise organizations. With a focus on performance, flexibility, and seamless user experiences, Rigby delivers composable commerce platforms designed for long-term growth.

Key Services

• Medusa.js Development

• Headless Commerce Development

• Next.js Storefront Development

• Custom eCommerce Application Development

• API & Third-Party Integrations

• Payment & Shipping Gateway Integrations

• Performance Optimization

• Ongoing Maintenance & Technical Support

3. Lambda Curry

Lambda Curry is a software development agency that helps businesses build scalable eCommerce platforms and modern web applications using technologies such as Medusa.js, Next.js, React, and Node.js. The agency focuses on delivering API-first, headless commerce solutions that provide flexibility, performance, and seamless customer experiences. From custom storefront development to backend integrations and ongoing optimization, Lambda Curry enables businesses to create future-ready digital commerce platforms tailored to their growth objectives.

Key Services

• Medusa.js Development

• Headless Commerce Architecture

• Next.js & React Storefront Development

• Custom eCommerce Application Development

• API & Third-Party Integrations

• Payment & Shipping Gateway Integrations

• Performance & Scalability Optimization

• Ongoing Maintenance & Technical Support

Final Thoughts

Medusa.js has emerged as one of the leading open-source commerce platforms for businesses seeking flexibility, ownership, and scalability. Whether you're building a D2C storefront, B2B commerce platform, or online marketplace, working with an experienced Medusa.js agency ensures your solution is built on a modern, composable architecture designed for long-term growth.